The Department of Biotechnology at Ramniranjan Jhunjhunwala College, Ghatkopar, Mumbai was setup in 2002 in response to the drive to initiate Biotechnology based programmes at the undergraduate level. The Department offers both undergraduate (B.Sc) and postgraduate (Ph.D) programmes. The B.Sc programme covers diverse but key courses from biological and engineering sciences that help the students to understand how the science of lives could be utilized to meet the challenges in current and future technological endeavours.

The Department of Biotechnology established undergraduate course in 2002  and postgraduate courses were introduced in 2005. The department was granted recognition for admitting students for M.Sc. (By research) and Ph.D in 2008